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Canadian Family Physician Medecin de... Nov 2009To discover the best treatments for acute infective conjunctivitis and to discern whether antibiotics are necessary for the resolution of bacterial conjunctivitis in... (Review)
Review
OBJECTIVE
To discover the best treatments for acute infective conjunctivitis and to discern whether antibiotics are necessary for the resolution of bacterial conjunctivitis in particular.
QUALITY OF EVIDENCE
MEDLINE, EMBASE, and the Cochrane Database of Systematic reviews were searched. Findings were limited to full-text articles from core clinical journals in the English language, and are based on level I or level II evidence. Clinical Evidence was also searched, from which moderate-quality results have been cited.
MAIN MESSAGE
Infective conjunctivitis should be managed conservatively, with antibiotics prescribed either after a delayed period if symptoms do not improve within 3 days of onset, or not at all. This approach helps to prevent the medicalization of the condition (reducing consultations for future occurrences) and discourages the unnecessary use of antibiotics, which might delay diagnosis of other serious red eye conditions. Physicians and patients should be educated on the self-limiting nature of the condition to increase compliance with conservative treatment and change the management expectations of parents and schools.
CONCLUSION
Acute infective conjunctivitis is the most common ocular complaint dealt with in family practice; its viral and bacterial etiologies are difficult to distinguish on clinical grounds alone. Evidence suggests that properly educating patients with written information materials is the most effective way to manage this simple ailment and increase patient satisfaction.
Topics: Anti-Bacterial Agents; Conjunctivitis, Bacterial; Drug Prescriptions; Evidence-Based Medicine; Family Practice; Humans; Practice Patterns, Physicians'
PubMed: 19910590
DOI: No ID Found -
IDCases 2023Primary meningococcal conjunctivitis from is a rare cause for acute, purulent conjunctivitis most commonly presenting in children. Here we present a case of primary...
Primary meningococcal conjunctivitis from is a rare cause for acute, purulent conjunctivitis most commonly presenting in children. Here we present a case of primary meningococcal conjunctivitis in an adult patient with mild signs/symptoms mimicking non-gonococcal bacterial conjunctivitis. The patient was immediately treated with topical and systemic antibiotics. Here we highlight that an early diagnosis of a mild case can be missed thus, clinicians need to keep a high index of suspension as prompt recognition is important to initiate appropriate systemic antimicrobial therapy to prevent systemic disease.
PubMed: 37063785
DOI: 10.1016/j.idcr.2023.e01749 -
BMJ Case Reports Jan 2022Giant fornix syndrome (GFS) results in chronic, relapsing conjunctivitis in elderly patients with enophthalmos and enlarged fornices, in which infectious material...
Giant fornix syndrome (GFS) results in chronic, relapsing conjunctivitis in elderly patients with enophthalmos and enlarged fornices, in which infectious material collects and perpetuates inflammation. A 98-year-old woman presented with persistent, bilateral, purulent conjunctivitis; corneal epithelial defects and progressive blepharospasm that did not respond to artificial tears, topical antibiotics and steroids and amniotic membrane grafts. Additional findings of deep-set orbits with enlarged upper fornices were diagnostic of GFS. Over the next 2 months, she responded to a combination of topical and systemic antibiotics, autologous serum eye drops, povidone-iodine forniceal rinses, and hypochlorous acid treatment of the eyelashes. GFS is an important diagnostic consideration in elderly patients with chronic conjunctivitis and deep-set orbits.
Topics: Aged; Aged, 80 and over; Conjunctival Diseases; Conjunctivitis; Conjunctivitis, Bacterial; Female; Humans; Lubricant Eye Drops; Povidone-Iodine; Staphylococcal Infections
PubMed: 35027379
DOI: 10.1136/bcr-2021-245460 -
International Journal of Ophthalmology 2019To evaluate the relative efficacy and safety of besifloxacin for treatment of acute bacterial conjunctivitis.
AIM
To evaluate the relative efficacy and safety of besifloxacin for treatment of acute bacterial conjunctivitis.
METHODS
A comprehensive search in PubMed, EMBASE Web of Science, Cochrane Central Database and CNKI was undertaken for randomized controlled trials (RCTs) comparing besifloxacin with other treatments or placebo. The primary outcome measures were clinical resolution, rates of bacterial eradication, individual clinical outcomes, cure rates, and bacterial eradication rates of different kinds of pathogens. Safety outcomes were the number of adverse effects (AEs). The final search was performed on August 2018.
RESULTS
Six RCTs were included. Four studies compared the efficacy and safety of besifloxacin with placebo, 1 study compared besifloxacin with moxifloxacin, and 1 study compared besifloxacin with gatifloxacin. A total of 2780 patients met the inclusion criteria. Besifloxacin presented higher efficacy and safety than did placebo in clinical resolution, rates of bacterial eradication, individual clinical outcomes, cure rates, bacterial eradication rates of different kinds of pathogens and the number of AEs. There was no significant difference between besifloxacin and moxifloxacin or gatifloxacin in the comparison items mentioned above.
CONCLUSION
Besifloxacin is highly effective and safe for treatment of acute bacterial conjunctivitis. Further comparative trials regarding the effect of besifloxacin for treatment of acute bacterial conjunctivitis will aid in treatment decisions.
PubMed: 31850176
DOI: 10.18240/ijo.2019.12.13 -
Eastern Mediterranean Health Journal =... Jun 2020Since the 1950s, the Kingdom of Morocco has been and remains one of the pioneers in the fight against trachoma, a disease that has completely disappeared in the majority... (Review)
Review
Since the 1950s, the Kingdom of Morocco has been and remains one of the pioneers in the fight against trachoma, a disease that has completely disappeared in the majority of its national territory, but some endemic pockets have persisted and pose a health risk, particularly for children and women. Morocco finds itself today, thanks to years of joint efforts, at the forefront of the world stage of the fight against trachoma. The country has demonstrated through its experience the effectiveness and relevance of the "SAFE" strategy - an extensive programme designed to tackle trachoma and its complications. The strategy is complex in its implementation and requires the synergy of a set of actors dedicated to specific activities, whether medico-surgical management activities aimed at setting up a physical project for local development, or information and awareness-raising activities. The key to the long-term success of eliminating blinding trachoma was not only to link distribution of drugs to the entire project area for several years to reduce substantially the reservoir of human- to-human transmission, but also to ensure permanence. In addition, services that provide quality palpebral surgery and especially repeat treatment campaigns with antibiotics, as well as health education campaigns and the promotion of personal and collective hygiene have generated sustainable changes in the living environment of receiving populations.
Topics: Anti-Bacterial Agents; Disease Eradication; Humans; Morocco; Trachoma
PubMed: 32621507
DOI: 10.26719/emhj.19.014 -
The National Medical Journal of India 1997
Topics: Conjunctivitis, Bacterial; Diphtheria; Humans
PubMed: 9401393
DOI: No ID Found -
BMJ (Clinical Research Ed.) Jul 2001
Meta-Analysis
Topics: Anti-Bacterial Agents; Child; Child, Preschool; Chlamydia trachomatis; Developing Countries; Humans; Hygiene; Infant; Insecticides; Randomized Controlled Trials as Topic; Trachoma
PubMed: 11473918
DOI: 10.1136/bmj.323.7306.218 -
Bulletin of the World Health... 1998
Topics: Global Health; Humans; Infection Control; Trachoma
PubMed: 10063695
DOI: No ID Found -
Proceedings of the Royal Society of... Nov 1972
Topics: Child, Preschool; Chlamydia; Conjunctivitis, Inclusion; Cornea; Humans; Hygiene; Infant, Newborn; Infant, Newborn, Diseases; Keratoconjunctivitis; Tetracycline; Trachoma
PubMed: 4642019
DOI: No ID Found -
Beyoglu Eye Journal 2019Subconjunctival abscess is a rare form of ocular infections. Subconjunctival abscesses often develop in the eyes with previous surgery or trauma. It is extremely rare in...
Subconjunctival abscess is a rare form of ocular infections. Subconjunctival abscesses often develop in the eyes with previous surgery or trauma. It is extremely rare in patients without surgery or trauma. In this study, we aimed to present a rare case of subconjunctival abscesses associated with spontaneous bacterial conjunctivitis. The patient was admitted to the hospital with complaints of redness, swelling and burning in two eyes. He said he used antibiotic drops for about a week, but his complaints did not decline. A subconjunctival abscess was detected in the right eye. There was no history of previous ocular surgery and trauma. Abscess drainage and subconjunctival antibiotic injection were performed. Oral and topical antibiotics were prescribed. There was no growth in culture. The third week was a complete recovery. In conclusion, spontaneous subconjunctival abscess formation should be considered in the differential diagnosis in unhealed eyes after bacterial conjunctivitis.
PubMed: 35187461
DOI: 10.14744/bej.2019.72691